About Carvedilol Beta Blocker With Alpha- Adrenergic Blocking Activity, Antihypertensive and Anti angina. Mechanism of Action of Carvedilol Carvedilol is an adrenergic antagonist capable of blocking alpha-1, beta-1, and beta-2 receptors. It produces vasodilatation through alpha-1 blockade as well as direct action. It decreases peripheral resistance, heart rate and blood pressure. It prevents reflex tachycardia. It also exerts it`s pharmacological actions through additional actions like Ca2+ entry blockade , anti oxidant action, antiproliferative action, & membrane stabilizing action. It does not harm lipid profile.Carvedilol improves ventricular function and reduces morbidity and mortality in patients with congestive heart failure. Indications for Carvedilol 1.Hypertension 2.Congestive heart failure 3.Stable angina pectoris