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Pegasys 180mcg
- Scientific Name: Peg inteferonum alfa-za 180 mcg / ml.
- Drag Period: once every week
- Type: Ampoules
- Producing Company: Roche
Medicine Description
Indication For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma. Mechanism of action Interferon alpha binds to type I interferon receptors (IFNAR1 and IFNAR2c) which, upon dimerization, activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription) which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon alpha binds less stably to type I interferon receptors than interferon beta.
Price: 22.15 Dinar.
- Shipping to Gulf Countries
Medicine Description
Indication For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma. Mechanism of action Interferon alpha binds to type I interferon receptors (IFNAR1 and IFNAR2c) which, upon dimerization, activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription) which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon alpha binds less stably to type I interferon receptors than interferon beta.
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